ADK anticorps (AA 165-351)

N° du produit ABIN7600222

L’anticorps Souris Monoclonal anti-ADK a été validé pour WB, IHC et FACS. Il convient pour détecter ADK dans des échantillons de Humain.

Aperçu rapide pour ADK anticorps (AA 165-351) (ABIN7600222)

Antigène: ADK (Adenosine Kinase (ADK))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ADK est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Clone: 7F4

Détail du produit anti-ADK anticorps

Épitope: AA 165-351

Fonction: Anti-ADK Antibody Picoband® (monoclonal, 7F4)

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-ADK Antibody Picoband® (monoclonal, 7F4) (ABIN7600222). Tested in Flow Cytometry, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E. coli-derived human ADK recombinant protein (Position: K165-T351). Human ADK shares 88.8% and 88.2% amino acid (aa) sequence identity with mouse and rat ADK, respectively.

Isotype: IgG1

Information d'application

Indications d'application: Western blot, 0.1-0.5 μg/mL
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells
1. Boison D, Scheurer L, Zumsteg V, Rulicke T, Litynski P, Fowler B, Brandner S, Mohler H: Neonatal hepatic steatosis by disruption of the adenosine kinase gene. Proc Natl Acad Sci U S A 2002, 99: 6985-6990. 2. Fox IH, Kelley WN: The role of adenosine and 2'-deoxyadenosine in mammalian cells. Annu Rev Biochem 1978, 47: 655-686.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Détails sur ADK

Antigène: ADK (Adenosine Kinase (ADK))

Autre désignation: ADK

Sujet:

Synonyms: Adenosine kinase, AK, Adenosine 5'-phosphotransferase, ADK

Tissue Specificity: Widely expressed. Highest level in placenta, liver, muscle and kidney.

Background: This gene is an enzyme which catalyzes the transfer of the gamma-phosphate from ATP to adenosine, thereby serving as a regulator of concentrations of both extracellular adenosine and intracellular adenine nucleotides. Adenosine has widespread effects on the cardiovascular, nervous, respiratory, and immune systems and inhibitors of the enzyme could play an important pharmacological role in increasing intravascular adenosine concentrations and acting as anti-inflammatory agents. Multiple transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 45 kDa

ID gène: 132

UniProt: P55263

Pathways: Ribonucleoside Biosynthetic Process